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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK2
All Species:
13.64
Human Site:
S393
Identified Species:
37.5
UniProt:
P78362
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78362
NP_872633.1
688
77543
S393
H
I
E
N
G
P
F
S
L
E
Q
Q
L
D
D
Chimpanzee
Pan troglodytes
XP_001160812
687
77411
S392
H
I
E
N
G
P
F
S
L
E
Q
Q
L
D
D
Rhesus Macaque
Macaca mulatta
XP_001088614
687
77455
S392
H
I
E
N
G
P
F
S
L
E
Q
Q
L
D
D
Dog
Lupus familis
XP_849273
686
77402
L391
H
I
E
N
G
P
F
L
L
E
Q
Q
L
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O54781
681
76738
S391
H
I
E
N
G
P
F
S
L
E
Q
Q
L
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508534
693
78060
L397
H
L
D
N
G
Q
F
L
L
E
Q
Q
I
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165329
695
78154
C400
H
L
E
N
G
P
F
C
V
E
S
Q
L
E
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
K485
P
N
D
I
G
C
H
K
V
V
Q
L
L
D
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
G436
N
N
N
S
I
N
N
G
I
G
I
K
N
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.6
N.A.
93.9
N.A.
N.A.
87.8
N.A.
80.7
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
99.4
99.2
96.5
N.A.
95.4
N.A.
N.A.
91.9
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
60
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
0
0
0
0
0
0
0
56
78
% D
% Glu:
0
0
67
0
0
0
0
0
0
78
0
0
0
34
12
% E
% Phe:
0
0
0
0
0
0
78
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
89
0
0
12
0
12
0
0
0
0
0
% G
% His:
78
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
56
0
12
12
0
0
0
12
0
12
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% K
% Leu:
0
23
0
0
0
0
0
23
67
0
0
12
78
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
23
12
78
0
12
12
0
0
0
0
0
12
0
12
% N
% Pro:
12
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
78
78
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
0
45
0
0
12
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
23
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _